Disease: Rectal Neoplasms
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
ETV4 P43268 ETS variant transcription factor 4 Transcription factor 2.9E-08 0.545 0.500
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LEP P41159 leptin 0.46 0.349 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846