Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
CD34 | P28906 | CD34 molecule | 5.0E-06 | 0.368 | 0.808 | |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
EPO | P01588 | erythropoietin | 1.1E-02 | 0.381 | 0.885 | |
GSTM1 | P09488 | glutathione S-transferase mu 1 | 2.1E-03 | 0.380 | 0.923 | |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
GSTT1 | P30711 | glutathione S-transferase theta 1 | 1.5E-04 | 0.393 | 0.923 | |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
ERCC2 | P18074 | ERCC excision repair 2, TFIIH core complex helicase subunit | Enzyme | 7.1E-20 | 0.420 | 0.846 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
RAF1 | P04049 | Raf-1 proto-oncogene, serine/threonine kinase | Kinase | 0.85 | 0.418 | 0.885 |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
NCAM1 | P13591 | neural cell adhesion molecule 1 | 1.00 | 0.415 | 0.885 | |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
RUNX1 | Q01196 | RUNX family transcription factor 1 | Transcription factor | 0.65 | 0.425 | 0.808 |
BCR | P11274 | BCR activator of RhoGEF and GTPase | Enzyme modulator | 0.99 | 0.431 | 0.885 |
CD19 | P15391 | CD19 molecule | 0.90 | 0.430 | 0.885 | |
RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
DNMT3A | Q9Y6K1 | DNA methyltransferase 3 alpha | 7.4E-39 | 0.445 | 0.846 |