Disease: Multiple Endocrine Neoplasia Type 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SST P61278 somatostatin Signaling 0.34 0.399 0.885
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
PSMD9 O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 4.9E-06 0.435 0.846
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
TICAM2 Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 2.6E-03 0.438 0.769
TMED7-TICAM2 Q86XR7 Q9Y3B3 TMED7-TICAM2 readthrough 2.6E-03 0.438 0.769
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
ZNRD2 O60232 zinc ribbon domain containing 2 1.8E-07 0.443 0.769
H3P23 H3 histone pseudogene 23 0.443 0.769
MEN1 O00255 menin 1 1.00 0.444 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808