Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
SST P61278 somatostatin Signaling 0.34 0.399 0.885
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846