Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
TYR P14679 tyrosinase Enzyme 5.0E-32 0.473 0.808
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885
SMO Q99835 smoothened, frizzled class receptor G-protein coupled receptor 4.3E-07 0.489 0.731
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846
KRT5 P13647 keratin 5 0.64 0.512 0.731
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
KRT17 Q04695 keratin 17 1.1E-11 0.531 0.654
PTCH2 Q9Y6C5 patched 2 3.4E-16 0.563 0.692
CLPTM1L Q96KA5 CLPTM1 like Enzyme 4.4E-05 0.551 0.654
LATS1 O95835 large tumor suppressor kinase 1 Kinase 1.00 0.563 0.731
ASIP P42127 agouti signaling protein Signaling 1.6E-02 0.584 0.692
SLC45A2 Q9UMX9 solute carrier family 45 member 2 Transporter 1.7E-06 0.626 0.538