Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
CXCR4 | P61073 | C-X-C motif chemokine receptor 4 | G-protein coupled receptor | 1.8E-02 | 0.362 | 0.923 |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
AQP1 | P29972 | aquaporin 1 (Colton blood group) | Ion channel | 2.6E-07 | 0.467 | 0.885 |
MBD2 | Q9UBB5 | methyl-CpG binding domain protein 2 | Epigenetic regulator | 0.35 | 0.466 | 0.846 |
KDM6B | O15054 | lysine demethylase 6B | Epigenetic regulator | 1.00 | 0.514 | 0.808 |
MTAP | Q13126 | methylthioadenosine phosphorylase | Enzyme | 7.6E-08 | 0.514 | 0.731 |
MSLN | Q13421 | mesothelin | Extracellular structure | 5.9E-25 | 0.525 | 0.692 |
CALB2 | P22676 | calbindin 2 | Calcium-binding protein | 4.5E-07 | 0.545 | 0.692 |
BST1 | Q10588 | bone marrow stromal cell antigen 1 | Enzyme | 4.2E-11 | 0.670 | 0.423 |