Disease: Endocardial Cushion Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731
AVSD1 atrioventricular septal defect 1 0.751 0.192
BAZ2B Q9UIF8 bromodomain adjacent to zinc finger domain 2B 0.98 0.839 0.192
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CEMIP2 Q9UHN6 cell migration inducing hyaluronidase 2 4.7E-13 0.861 0.231
ETV5 P41161 ETS variant transcription factor 5 Transcription factor 1.00 0.565 0.731
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
HAND2 P61296 heart and neural crest derivatives expressed 2 0.40 0.612 0.500
HEY2 Q9UBP5 hes related family bHLH transcription factor with YRPW motif 2 Transcription factor 0.89 0.572 0.731
IFT172 Q9UG01 intraflagellar transport 172 Cellular structure 3.3E-33 0.582 0.654
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
MYL7 Q01449 myosin light chain 7 Calcium-binding protein 1.8E-06 0.760 0.231
NFATC1 O95644 nuclear factor of activated T cells 1 Transcription factor 0.16 0.517 0.731
NPNT Q6UXI9 nephronectin 2.7E-10 0.659 0.654
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808
RBM24 Q9BX46 RNA binding motif protein 24 8.6E-02 0.760 0.346
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
SALL4 Q9UJQ4 spalt like transcription factor 4 Transcription factor 1.00 0.489 0.769
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
TBX2 Q13207 T-box transcription factor 2 Transcription factor 0.99 0.544 0.769
TBX5 Q99593 T-box transcription factor 5 Transcription factor 1.00 0.528 0.769