Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
TGFA | P01135 | transforming growth factor alpha | Signaling | 0.72 | 0.432 | 0.885 |
MMP14 | P50281 | matrix metallopeptidase 14 | Enzyme | 1.00 | 0.447 | 0.769 |
PAX3 | P23760 | paired box 3 | 0.24 | 0.481 | 0.769 | |
KITLG | P21583 | KIT ligand | 0.85 | 0.473 | 0.885 | |
IRF4 | Q15306 | interferon regulatory factor 4 | Transcription factor | 0.86 | 0.491 | 0.769 |
PDK1 | Q15118 | pyruvate dehydrogenase kinase 1 | Kinase | 1.1E-05 | 0.510 | 0.808 |
OCA2 | Q04671 | OCA2 melanosomal transmembrane protein | 2.9E-13 | 0.539 | 0.808 | |
PRAME | P78395 | preferentially expressed antigen in melanoma | 2.4E-07 | 0.531 | 0.577 | |
TFE3 | P19532 | transcription factor binding to IGHM enhancer 3 | 0.98 | 0.542 | 0.654 | |
CMM | cutaneous malignant melanoma/dysplastic nevus | 0.670 | 0.385 |