Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
H3P10 H3 histone pseudogene 10 0.350 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
VIM P08670 vimentin 0.71 0.372 0.846
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808