Disease: Hypertriglyceridemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
ARNT P27540 aryl hydrocarbon receptor nuclear translocator Transcription factor 1.00 0.575 0.692
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
CPT2 P23786 carnitine palmitoyltransferase 2 Enzyme 4.6E-10 0.542 0.769
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577