Disease: Hypertriglyceridemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
CPT2 P23786 carnitine palmitoyltransferase 2 Enzyme 4.6E-10 0.542 0.769
MLXIPL Q9NP71 MLX interacting protein like 4.8E-02 0.554 0.731
CPT1A P50416 carnitine palmitoyltransferase 1A Enzyme 5.1E-09 0.555 0.808
PNPLA3 Q9NST1 patatin like phospholipase domain containing 3 Enzyme 5.7E-08 0.556 0.692
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
ARNT P27540 aryl hydrocarbon receptor nuclear translocator Transcription factor 1.00 0.575 0.692
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
APOA5 Q6Q788 apolipoprotein A5 5.6E-10 0.587 0.615
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615
ILF3 Q12906 interleukin enhancer binding factor 3 Nucleic acid binding 1.00 0.621 0.654
SYNE2 Q8WXH0 spectrin repeat containing nuclear envelope protein 2 1.7E-25 0.623 0.692