Disease: Hypertriglyceridemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
CPT2 P23786 carnitine palmitoyltransferase 2 Enzyme 4.6E-10 0.542 0.769
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
ARNT P27540 aryl hydrocarbon receptor nuclear translocator Transcription factor 1.00 0.575 0.692
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
CPT1A P50416 carnitine palmitoyltransferase 1A Enzyme 5.1E-09 0.555 0.808
APOC4 P55056 apolipoprotein C4 8.9E-08 0.743 0.385
RP1 P56715 RP1 axonemal microtubule associated 4.4E-13 0.663 0.462
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
ILF3 Q12906 interleukin enhancer binding factor 3 Nucleic acid binding 1.00 0.621 0.654
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615
APOA5 Q6Q788 apolipoprotein A5 5.6E-10 0.587 0.615
ANGPTL8 Q6UXH0 angiopoietin like 8 6.9E-12 0.650 0.577
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
SYNE2 Q8WXH0 spectrin repeat containing nuclear envelope protein 2 1.7E-25 0.623 0.692
DOCK7 Q96N67 dedicator of cytokinesis 7 Enzyme modulator 6.4E-06 0.682 0.423
BUD13 Q9BRD0 BUD13 homolog 2.1E-06 0.751 0.538