Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
FLNA P21333 filamin A 1.00 0.419 0.846
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
ENG P17813 endoglin 1.00 0.446 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
STIM1 Q13586 stromal interaction molecule 1 0.78 0.501 0.808
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731