Disease: Geographic Atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
AMD1 P17707 adenosylmethionine decarboxylase 1 Enzyme 0.98 0.593 0.577
AMD1P2 adenosylmethionine decarboxylase 1 pseudogene 2 0.608 0.538
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARMS2 P0C7Q2 age-related maculopathy susceptibility 2 5.2E-04 0.670 0.308
C2 P06681 complement C2 1.3E-16 0.617 0.692
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
CD200 P41217 CD200 molecule 0.41 0.529 0.769
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CFB P00751 complement factor B 4.7E-16 0.532 0.769
CFH P08603 complement factor H 0.86 0.441 0.885
CFI P05156 complement factor I 3.5E-08 0.569 0.731
COL8A1 P27658 collagen type VIII alpha 1 chain Extracellular structure 0.41 0.678 0.538
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885
HTRA1 Q92743 HtrA serine peptidase 1 Enzyme 4.9E-04 0.532 0.692
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808
SKIV2L Q15477 Ski2 like RNA helicase 1.3E-22 0.615 0.654
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SRPK2 P78362 SRSF protein kinase 2 Kinase 1.00 0.653 0.423
TLR3 O15455 toll like receptor 3 Receptor 1.6E-07 0.427 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923