Disease: Neoplasms, Intracranial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
IQGAP1 P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 1.00 0.560 0.692
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
LEP P41159 leptin 0.46 0.349 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923