Disease: HER2 gene amplification
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NEURL1 O76050 neuralized E3 ubiquitin protein ligase 1 Enzyme 1.1E-02 0.556 0.538
NCOA3 Q9Y6Q9 nuclear receptor coactivator 3 Kinase 0.54 0.522 0.654
EREG O14944 epiregulin Signaling 1.2E-05 0.554 0.692
GAB2 Q9UQC2 GRB2 associated binding protein 2 Receptor 0.98 0.563 0.692
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
NEU1 Q99519 neuraminidase 1 Enzyme 7.3E-05 0.513 0.769
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
RARA P10276 retinoic acid receptor alpha Nuclear receptor 0.96 0.470 0.846
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885