Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846