Disease: HER2-positive carcinoma of breast
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ETV4 P43268 ETS variant transcription factor 4 Transcription factor 2.9E-08 0.545 0.500
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
GAB2 Q9UQC2 GRB2 associated binding protein 2 Receptor 0.98 0.563 0.692
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
GRB2 P62993 growth factor receptor bound protein 2 0.94 0.546 0.769
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
HUNK P57058 hormonally up-regulated Neu-associated kinase Kinase 1.00 0.821 0.115
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MST1R Q04912 macrophage stimulating 1 receptor Kinase 7.9E-37 0.542 0.808
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962