Disease: Primary cholangiocarcinoma of intrahepatic biliary tract
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FABP5 Q01469 fatty acid binding protein 5 4.7E-02 0.585 0.731
GRB2 P62993 growth factor receptor bound protein 2 0.94 0.546 0.769
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
ITGA3 P26006 integrin subunit alpha 3 3.6E-07 0.573 0.731
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923