Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
MIR155 | microRNA 155 | 0.384 | 0.885 | |||
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | |
TIMP3 | P35625 | TIMP metallopeptidase inhibitor 3 | Enzyme modulator | 0.63 | 0.445 | 0.923 |
IDO1 | P14902 | indoleamine 2,3-dioxygenase 1 | 3.3E-06 | 0.454 | 0.846 | |
RRAS | P10301 | RAS related | Enzyme modulator | 4.7E-03 | 0.543 | 0.808 |
HRK | O00198 | harakiri, BCL2 interacting protein | 0.36 | 0.769 | 0.269 |