Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | |
MMP1 | P03956 | matrix metallopeptidase 1 | Enzyme | 7.7E-18 | 0.385 | 0.885 |
ELN | P15502 | elastin | 2.1E-14 | 0.415 | 0.885 | |
SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
FOXO3 | O43524 | forkhead box O3 | 0.99 | 0.431 | 0.808 | |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
COPD | Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 | |||
MMP14 | P50281 | matrix metallopeptidase 14 | Enzyme | 1.00 | 0.447 | 0.769 |
CXCL1 | P09341 | C-X-C motif chemokine ligand 1 | Signaling | 0.12 | 0.449 | 0.923 |
HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | G-protein coupled receptor | 0.51 | 0.473 | 0.846 |
HDAC2 | Q92769 | histone deacetylase 2 | Epigenetic regulator | 1.00 | 0.476 | 0.846 |
CYP1A2 | P05177 | cytochrome P450 family 1 subfamily A member 2 | Enzyme | 2.5E-10 | 0.494 | 0.923 |
EPHX1 | P07099 | epoxide hydrolase 1 | 3.2E-09 | 0.500 | 0.846 | |
SFTPD | P35247 | surfactant protein D | Surfactant | 7.5E-05 | 0.500 | 0.846 |
DSP | P15924 | desmoplakin | Cellular structure | 1.00 | 0.514 | 0.808 |
CXCL2 | P19875 | C-X-C motif chemokine ligand 2 | Signaling | 3.6E-07 | 0.513 | 0.885 |