Disease: invasive cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SCT P09683 secretin 1.4E-07 0.484 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
SRC P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 1.00 0.467 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654