Disease: Germ cell tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
PIWIL1 Q96J94 piwi like RNA-mediated gene silencing 1 7.3E-14 0.570 0.731
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
PIWIL2 Q8TC59 piwi like RNA-mediated gene silencing 2 2.7E-08 0.612 0.577
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
PDPN Q86YL7 podoplanin 3.2E-04 0.470 0.769
PTTG1 O95997 PTTG1 regulator of sister chromatid separation, securin 4.2E-04 0.526 0.654
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MAD2L1 Q13257 mitotic arrest deficient 2 like 1 9.3E-03 0.575 0.615
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
CDH1 P12830 cadherin 1 0.15 0.401 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923