Disease: Adenocarcinoma of prostate
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR21 microRNA 21 0.363 0.846
TMPRSS2 O15393 transmembrane serine protease 2 Enzyme 2.4E-10 0.615 0.500
SIAH2 O43255 siah E3 ubiquitin protein ligase 2 0.69 0.633 0.538
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
SPINK1 P00995 serine peptidase inhibitor Kazal type 1 0.31 0.492 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885