Disease: HER2 gene amplification
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
HMGA1 P17096 high mobility group AT-hook 1 Nucleic acid binding 0.83 0.494 0.769
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NEU1 Q99519 neuraminidase 1 Enzyme 7.3E-05 0.513 0.769
NEURL1 O76050 neuralized E3 ubiquitin protein ligase 1 Enzyme 1.1E-02 0.556 0.538