Disease: Hepatolenticular Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
AHCY P23526 adenosylhomocysteinase Enzyme 3.6E-02 0.582 0.692
ANKS1B Q7Z6G8 ankyrin repeat and sterile alpha motif domain containing 1B Receptor 1.00 0.686 0.423
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ASMT P46597 acetylserotonin O-methyltransferase 1.3E-20 0.691 0.346
ATP7B P35670 ATPase copper transporting beta Transporter 4.8E-30 0.529 0.654
BHMT Q93088 betaine--homocysteine S-methyltransferase 3.7E-14 0.595 0.731
CAMK2A Q9UQM7 calcium/calmodulin dependent protein kinase II alpha Kinase 1.00 0.612 0.538
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
LOX P28300 lysyl oxidase 0.99 0.447 0.846
LOXL2 Q9Y4K0 lysyl oxidase like 2 3.4E-07 0.527 0.731
NDUFB7 P17568 NADH:ubiquinone oxidoreductase subunit B7 Enzyme 3.2E-03 0.890 0.192
PPP3CA Q08209 protein phosphatase 3 catalytic subunit alpha 1.00 0.568 0.769
PPP3CB P16298 protein phosphatase 3 catalytic subunit beta 1.00 0.760 0.308
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
SDHAF2 Q9NX18 succinate dehydrogenase complex assembly factor 2 2.8E-06 0.604 0.692
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962