Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
SLC35A2 P78381 solute carrier family 35 member A2 Transporter 0.72 0.525 0.808
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
KDM5B Q9UGL1 lysine demethylase 5B Epigenetic regulator 7.9E-15 0.532 0.731
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
CRBN Q96SW2 cereblon Enzyme 2.9E-04 0.551 0.654
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808
SARS1 P49591 seryl-tRNA synthetase 1 Enzyme 1.00 0.558 0.769
NSUN2 Q08J23 NOP2/Sun RNA methyltransferase 2 Enzyme 2.6E-04 0.559 0.846
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769
AIMP1 Q12904 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Enzyme 3.0E-07 0.566 0.769
TUSC3 Q13454 tumor suppressor candidate 3 Transporter 3.5E-06 0.576 0.615
B3GALNT2 Q8NCR0 beta-1,3-N-acetylgalactosaminyltransferase 2 Enzyme 2.8E-07 0.578 0.577
HNMT P50135 histamine N-methyltransferase 2.0E-02 0.579 0.808
MED25 Q71SY5 mediator complex subunit 25 Transcription factor 8.4E-07 0.582 0.654
TRAPPC9 Q96Q05 trafficking protein particle complex 9 2.3E-14 0.603 0.577
ST3GAL3 Q11203 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 2.6E-03 0.606 0.654