Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
RAF1 | P04049 | Raf-1 proto-oncogene, serine/threonine kinase | Kinase | 0.85 | 0.418 | 0.885 |
MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
SOS1 | Q07889 | SOS Ras/Rac guanine nucleotide exchange factor 1 | Enzyme modulator | 1.00 | 0.485 | 0.808 |
EPHA2 | P29317 | EPH receptor A2 | Kinase | 1.1E-05 | 0.501 | 0.731 |
MAP2K2 | P36507 | mitogen-activated protein kinase kinase 2 | Kinase | 0.97 | 0.534 | 0.731 |
SHOC2 | Q9UQ13 | SHOC2 leucine rich repeat scaffold protein | 1.00 | 0.593 | 0.769 |