Disease: Pervasive Development Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CNTN4 Q8IWV2 contactin 4 Receptor 3.3E-06 0.653 0.577
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CUX2 O14529 cut like homeobox 2 Transcription factor 1.00 0.644 0.500
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
DMXL2 Q8TDJ6 Dmx like 2 1.00 0.695 0.538
EEF1A2 Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 1.00 0.554 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
EN2 P19622 engrailed homeobox 2 Transcription factor 0.63 0.674 0.462
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808
FOXP2 O15409 forkhead box P2 1.00 0.545 0.808
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GPHN Q9NQX3 gephyrin 1.00 0.608 0.538
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GRM7 Q14831 glutamate metabotropic receptor 7 G-protein coupled receptor 1.00 0.628 0.538
HERC2 O95714 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.00 0.568 0.692
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500