Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
IL4 | P05112 | interleukin 4 | 4.7E-03 | 0.332 | 0.962 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
IL2 | P60568 | interleukin 2 | 0.48 | 0.336 | 0.885 | |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
CXCR4 | P61073 | C-X-C motif chemokine receptor 4 | G-protein coupled receptor | 1.8E-02 | 0.362 | 0.923 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |