Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
FAN1 Q9Y2M0 FANCD2 and FANCI associated nuclease 1 1.7E-25 0.610 0.577
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
RPS20 P60866 ribosomal protein S20 Nucleic acid binding 2.1E-02 0.610 0.692
POLR3B Q9NW08 RNA polymerase III subunit B Enzyme 1.7E-23 0.628 0.654
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923