Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
ALDH1A3 P47895 aldehyde dehydrogenase 1 family member A3 Enzyme 0.14 0.578 0.654
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BLVRB P30043 biliverdin reductase B Enzyme 4.2E-06 0.695 0.423
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMP7 P18075 bone morphogenetic protein 7 Signaling 0.13 0.498 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CA1 P00915 carbonic anhydrase 1 4.7E-11 0.623 0.769
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTNND1 O60716 catenin delta 1 Cellular structure 1.00 0.500 0.808
DES P17661 desmin 8.8E-03 0.460 0.846
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846
FBP1 P09467 fructose-bisphosphatase 1 Enzyme 7.9E-02 0.575 0.692
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808