Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
MTCO2P12 | MT-CO2 pseudogene 12 | 0.368 | 0.962 | |||
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
MMP1 | P03956 | matrix metallopeptidase 1 | Enzyme | 7.7E-18 | 0.385 | 0.885 |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
CCN2 | P29279 | cellular communication network factor 2 | Signaling | 5.0E-04 | 0.399 | 0.846 |
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
CDKN1A | P38936 | cyclin dependent kinase inhibitor 1A | 1.9E-03 | 0.403 | 0.769 | |
MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |
RPE65 | Q16518 | retinoid isomerohydrolase RPE65 | Enzyme | 6.5E-14 | 0.417 | 0.808 |
BMP4 | P12644 | bone morphogenetic protein 4 | Signaling | 0.96 | 0.422 | 0.808 |
RUNX2 | Q13950 | RUNX family transcription factor 2 | Transcription factor | 0.95 | 0.437 | 0.846 |
HSPG2 | P98160 | heparan sulfate proteoglycan 2 | Enzyme modulator | 1.0E-19 | 0.438 | 0.885 |