Disease: Leukemia, B-Cell
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCL6 P41182 BCL6 transcription repressor 0.96 0.444 0.808
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CD19 P15391 CD19 molecule 0.90 0.430 0.885
CD22 P20273 CD22 molecule 0.80 0.556 0.615
CD33 P20138 CD33 molecule Receptor 5.7E-07 0.524 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
MIR21 microRNA 21 0.363 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
MTTP P55157 microsomal triglyceride transfer protein Transporter 1.0E-05 0.505 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIM1 P11309 Pim-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.482 0.769