Disease: Clinodactyly of the 5th finger
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
ANKRD11 Q6UB99 ankyrin repeat domain 11 1.00 0.556 0.808
BPTF Q12830 bromodomain PHD finger transcription factor 1.00 0.560 0.769
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BUB1 O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 4.9E-09 0.528 0.731
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
BUB3 O43684 BUB3 mitotic checkpoint protein Nucleic acid binding 0.81 0.588 0.615
CCDC8 Q9H0W5 coiled-coil domain containing 8 0.25 0.599 0.692
CDC6 Q99741 cell division cycle 6 1.1E-09 0.552 0.731
CEP57 Q86XR8 centrosomal protein 57 7.3E-02 0.615 0.615
CUL7 Q14999 cullin 7 2.6E-21 0.633 0.500
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
EBF3 Q9H4W6 EBF transcription factor 3 1.00 0.595 0.731
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
H19 H19 imprinted maternally expressed transcript 0.494 0.923
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
KCNJ2 P63252 potassium inwardly rectifying channel subfamily J member 2 Ion channel 0.31 0.572 0.731
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LEMD3 Q9Y2U8 LEM domain containing 3 1.00 0.582 0.731
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731