Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
NHS Q6T4R5 NHS actin remodeling regulator 1.00 0.466 0.846
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
PRDX1 Q06830 peroxiredoxin 1 Enzyme 7.7E-10 0.485 0.846
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808