Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
TPM3 P06753 tropomyosin 3 Cellular structure 6.7E-03 0.490 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
NHS Q6T4R5 NHS actin remodeling regulator 1.00 0.466 0.846
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808