Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
OFD1 | O75665 | OFD1 centriole and centriolar satellite protein | 0.96 | 0.510 | 0.808 | |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
TBX1 | O43435 | T-box transcription factor 1 | Transcription factor | 0.84 | 0.433 | 0.808 |
RYR1 | P21817 | ryanodine receptor 1 | Ion channel | 1.6E-29 | 0.489 | 0.808 |
DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | Enzyme | 3.9E-13 | 0.500 | 0.846 |
TTN | Q8WZ42 | titin | Kinase | 2.6E-96 | 0.470 | 0.885 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 | |
TMEM67 | Q5HYA8 | transmembrane protein 67 | 2.1E-24 | 0.512 | 0.769 | |
MYH7 | P12883 | myosin heavy chain 7 | 4.2E-16 | 0.516 | 0.692 | |
JMJD1C | Q15652 | jumonji domain containing 1C | 1.00 | 0.517 | 0.769 | |
MKS1 | Q9NXB0 | MKS transition zone complex subunit 1 | Extracellular structure | 3.4E-16 | 0.505 | 0.769 |
GP1BB | P13224 | glycoprotein Ib platelet subunit beta | 0.51 | 0.524 | 0.769 | |
CEP290 | O15078 | centrosomal protein 290 | 1.1E-60 | 0.517 | 0.769 | |
TPM2 | P07951 | tropomyosin 2 | Cellular structure | 2.4E-04 | 0.530 | 0.654 |
ATP7A | Q04656 | ATPase copper transporting alpha | Transporter | 1.00 | 0.494 | 0.769 |
RECQL4 | O94761 | RecQ like helicase 4 | Enzyme | 3.3E-35 | 0.496 | 0.808 |
KIF7 | Q2M1P5 | kinesin family member 7 | 2.3E-22 | 0.528 | 0.731 | |
SETBP1 | Q9Y6X0 | SET binding protein 1 | 1.00 | 0.503 | 0.808 |