Disease: Macrocephaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
SLC9A7 Q96T83 solute carrier family 9 member A7 Transporter 0.99 0.695 0.577
SLC26A2 P50443 solute carrier family 26 member 2 Transporter 7.5E-07 0.553 0.692
SIX2 Q9NPC8 SIX homeobox 2 Transcription factor 0.94 0.604 0.654
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
RIPPLY2 Q5TAB7 ripply transcriptional repressor 2 9.4E-03 0.650 0.462
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
ARHGEF6 Q15052 Rac/Cdc42 guanine nucleotide exchange factor 6 1.00 0.678 0.462
RAB39B Q96DA2 RAB39B, member RAS oncogene family 0.83 0.619 0.615
PIK3R2 O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 1.6E-02 0.551 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIGT Q969N2 phosphatidylinositol glycan anchor biosynthesis class T 7.3E-10 0.633 0.615
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
PIGA P37287 phosphatidylinositol glycan anchor biosynthesis class A 0.96 0.575 0.654
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731
PEX5 P50542 peroxisomal biogenesis factor 5 Transporter 5.6E-05 0.561 0.731
PEX3 P56589 peroxisomal biogenesis factor 3 1.6E-02 0.595 0.731
PEX26 Q7Z412 peroxisomal biogenesis factor 26 0.93 0.584 0.615
PEX2 P28328 peroxisomal biogenesis factor 2 2.6E-04 0.582 0.654
PEX19 P40855 peroxisomal biogenesis factor 19 Storage 3.2E-04 0.585 0.731
PEX16 Q9Y5Y5 peroxisomal biogenesis factor 16 8.3E-05 0.597 0.615