Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
IL17A | Q16552 | interleukin 17A | 4.3E-02 | 0.324 | 0.923 | |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
IL2 | P60568 | interleukin 2 | 0.48 | 0.336 | 0.885 | |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |