Disease: Downward slant of palpebral fissure
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SH3PXD2B A1X283 SH3 and PX domains 2B 4.2E-03 0.631 0.577
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
KDM1A O60341 lysine demethylase 1A Epigenetic regulator 1.00 0.512 0.808
LRP4 O75096 LDL receptor related protein 4 1.4E-06 0.568 0.692
GPC4 O75487 glypican 4 0.93 0.547 0.769
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
B3GAT3 O94766 beta-1,3-glucuronyltransferase 3 Enzyme 2.7E-08 0.621 0.538
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462
EFEMP2 O95967 EGF containing fibulin extracellular matrix protein 2 Calcium-binding protein 8.2E-03 0.559 0.692
APC2 O95996 APC regulator of WNT signaling pathway 2 1.00 0.582 0.654
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
MYH3 P11055 myosin heavy chain 3 6.7E-21 0.563 0.654
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
SON P18583 SON DNA binding protein 1.00 0.565 0.769
FLNA P21333 filamin A 1.00 0.419 0.846
TAF1 P21675 TATA-box binding protein associated factor 1 Kinase 1.00 0.581 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
PYCR1 P32322 pyrroline-5-carboxylate reductase 1 2.0E-04 0.570 0.654
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846