Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ATN1 P54259 atrophin 1 1.00 0.409 0.885
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846