Disease: Mixed anxiety and depressive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
TAL1 P17542 TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 0.57 0.505 0.731
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
SCLY Q96I15 selenocysteine lyase Enzyme 2.3E-09 0.530 0.731