Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
COL2A1 | P02458 | collagen type II alpha 1 chain | 1.00 | 0.444 | 0.846 | |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
COL11A2 | P13942 | collagen type XI alpha 2 chain | 0.70 | 0.435 | 0.846 | |
BCR | P11274 | BCR activator of RhoGEF and GTPase | Enzyme modulator | 0.99 | 0.431 | 0.885 |
WNT5A | P41221 | Wnt family member 5A | Signaling | 0.99 | 0.443 | 0.808 |
ENG | P17813 | endoglin | 1.00 | 0.446 | 0.846 | |
EHMT1 | Q9H9B1 | euchromatic histone lysine methyltransferase 1 | Epigenetic regulator | 1.00 | 0.460 | 0.808 |
ATP7A | Q04656 | ATPase copper transporting alpha | Transporter | 1.00 | 0.494 | 0.769 |
GPC3 | P51654 | glypican 3 | 1.00 | 0.466 | 0.808 | |
HDAC6 | Q9UBN7 | histone deacetylase 6 | Epigenetic regulator | 1.00 | 0.465 | 0.846 |
PIK3R1 | P27986 | phosphoinositide-3-kinase regulatory subunit 1 | Kinase | 1.00 | 0.477 | 0.885 |
MAP3K7 | O43318 | mitogen-activated protein kinase kinase kinase 7 | Kinase | 1.00 | 0.477 | 0.808 |
COL11A1 | P12107 | collagen type XI alpha 1 chain | 1.00 | 0.495 | 0.846 | |
GATA1 | P15976 | GATA binding protein 1 | 0.95 | 0.483 | 0.808 |