Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
CD34 | P28906 | CD34 molecule | 5.0E-06 | 0.368 | 0.808 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
IFNB1 | P01574 | interferon beta 1 | 0.421 | 0.846 | ||
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | |
MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 | |
SMARCA4 | P51532 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Epigenetic regulator | 1.00 | 0.450 | 0.885 |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
TH | P07101 | tyrosine hydroxylase | 1.7E-06 | 0.462 | 0.885 | |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
SRY | Q05066 | sex determining region Y | Transcription factor | 0.456 | 0.808 | |
TERC | telomerase RNA component | 0.471 | 0.846 | |||
CDX2 | Q99626 | caudal type homeobox 2 | Transcription factor | 0.53 | 0.458 | 0.769 |
PML | P29590 | promyelocytic leukemia | 0.21 | 0.477 | 0.846 |