Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
INS P01308 insulin 0.30 0.445 0.923
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
GCK P35557 glucokinase Kinase 0.63 0.523 0.808
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
ABCC9 O60706 ATP binding cassette subfamily C member 9 Transporter 9.4E-09 0.552 0.692
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
CEL P19835 carboxyl ester lipase 1.5E-06 0.514 0.808
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808