Disease: Sensorimotor neuropathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABHD12 Q8N2K0 abhydrolase domain containing 12 Enzyme 1.9E-05 0.666 0.385
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
B4GALNT1 Q00973 beta-1,4-N-acetyl-galactosaminyltransferase 1 3.9E-05 0.644 0.615
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
IGHMBP2 P38935 immunoglobulin mu DNA binding protein 2 3.0E-16 0.636 0.615
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
NEFL P07196 neurofilament light 0.488 0.769
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
SBF2 Q86WG5 SET binding factor 2 Enzyme 6.4E-10 0.619 0.577
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TDP1 Q9NUW8 tyrosyl-DNA phosphodiesterase 1 Enzyme 1.3E-17 0.612 0.538
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769