Disease: hearing impairment
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
B3GLCT Q6Y288 beta 3-glucosyltransferase Enzyme 7.1E-17 0.554 0.731
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
ORC4 O43929 origin recognition complex subunit 4 Nucleic acid binding 7.6E-13 0.612 0.654
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
MASP1 P48740 mannan binding lectin serine peptidase 1 Enzyme 1.2E-11 0.565 0.885
CDT1 Q9H211 chromatin licensing and DNA replication factor 1 2.6E-10 0.597 0.731
RFWD3 Q6PCD5 ring finger and WD repeat domain 3 Enzyme 3.5E-10 0.569 0.731
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
CDC6 Q99741 cell division cycle 6 1.1E-09 0.552 0.731
BUB1 O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 4.9E-09 0.528 0.731
PIGL Q9Y2B2 phosphatidylinositol glycan anchor biosynthesis class L 6.2E-09 0.581 0.731