Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | Transporter | 6.5E-06 | 0.518 | 0.692 |
SLC9A6 | Q92581 | solute carrier family 9 member A6 | Transporter | 1.00 | 0.516 | 0.846 |
VAPB | O95292 | VAMP associated protein B and C | Transporter | 0.58 | 0.666 | 0.423 |
TBP | P20226 | TATA-box binding protein | Transcription factor | 1.5E-02 | 0.552 | 0.846 |
PDYN | P01213 | prodynorphin | Signaling | 1.7E-04 | 0.535 | 0.577 |
VAC14 | Q08AM6 | VAC14 component of PIKFYVE complex | Receptor | 0.19 | 0.588 | 0.731 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
NR4A2 | P43354 | nuclear receptor subfamily 4 group A member 2 | Nuclear receptor | 1.00 | 0.529 | 0.846 |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
KCNT1 | Q5JUK3 | potassium sodium-activated channel subfamily T member 1 | Ion channel | 2.8E-05 | 0.610 | 0.308 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
SERPINI1 | Q99574 | serpin family I member 1 | Enzyme modulator | 2.7E-02 | 0.631 | 0.462 |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
SCO2 | O43819 | synthesis of cytochrome C oxidase 2 | Enzyme | 7.5E-07 | 0.479 | 0.846 |
CTSD | P07339 | cathepsin D | Enzyme | 9.2E-04 | 0.478 | 0.846 |
ADH1C | P00326 | alcohol dehydrogenase 1C (class I), gamma polypeptide | Enzyme | 0.547 | 0.731 | |
NARS2 | Q96I59 | asparaginyl-tRNA synthetase 2, mitochondrial | Enzyme | 7.1E-08 | 0.650 | 0.577 |
GLUD2 | P49448 | glutamate dehydrogenase 2 | Enzyme | 3.2E-02 | 0.678 | 0.423 |
TBCD | Q9BTW9 | tubulin folding cofactor D | Cellular structure | 1.0E-07 | 0.599 | 0.615 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 |