Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
SCO2 | O43819 | synthesis of cytochrome C oxidase 2 | Enzyme | 7.5E-07 | 0.479 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CTSD | P07339 | cathepsin D | Enzyme | 9.2E-04 | 0.478 | 0.846 |
FIG4 | Q92562 | FIG4 phosphoinositide 5-phosphatase | 2.3E-34 | 0.551 | 0.731 | |
BSCL2 | Q96G97 | BSCL2 lipid droplet biogenesis associated, seipin | 1.1E-09 | 0.545 | 0.692 | |
NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | Transporter | 6.5E-06 | 0.518 | 0.692 |
SLC9A6 | Q92581 | solute carrier family 9 member A6 | Transporter | 1.00 | 0.516 | 0.846 |
PDYN | P01213 | prodynorphin | Signaling | 1.7E-04 | 0.535 | 0.577 |
PSAP | P07602 | prosaposin | 0.99 | 0.532 | 0.846 | |
HTT | P42858 | huntingtin | 1.00 | 0.548 | 0.654 | |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
NR4A2 | P43354 | nuclear receptor subfamily 4 group A member 2 | Nuclear receptor | 1.00 | 0.529 | 0.846 |
TBP | P20226 | TATA-box binding protein | Transcription factor | 1.5E-02 | 0.552 | 0.846 |
ADH1C | P00326 | alcohol dehydrogenase 1C (class I), gamma polypeptide | Enzyme | 0.547 | 0.731 |